How to Use an EpiPen — Anaphylaxis Emergency Guide | KiwiMeds

💉 How to Use an EpiPen (Adrenaline Auto-Injector)

⚠️ For use in severe allergic reactions (anaphylaxis) only. Call 111 immediately after use.

🚨 This is an emergency medication
If you or someone nearby is having a severe allergic reaction (anaphylaxis) — swollen throat, difficulty breathing, collapse — use the EpiPen immediately and call 111. Do not wait to see if symptoms improve on their own.

Signs of Anaphylaxis — Use the EpiPen if You See:

  • Swelling of lips, tongue, or throat
  • Difficulty breathing or swallowing
  • Skin rash, hives, or widespread redness
  • Sudden drop in blood pressure, dizziness, or collapse
  • Nausea, vomiting, or abdominal pain after exposure to a known allergen

How to Use an EpiPen — Step by Step

  1. 1
    Call 111 first (or have someone call while you administer).
  2. 2
    Remove the EpiPen from its carrier tube. Hold it in your dominant hand with your thumb closest to the blue safety cap.
  3. 3
    Pull off the blue safety cap with your other hand. Do not put your thumb over the orange tip.
  4. 4
    Place the orange tip against the outer mid-thigh — you can inject through clothing. Hold firmly.
  5. 5
    Push down hard until you hear a click — this releases the needle and injects the adrenaline.
  6. 6
    Hold firmly for 10 seconds, then remove. Massage the injection site gently for 10 seconds.
  7. 7
    The orange tip will extend to cover the needle. Place the used EpiPen back in the carrier tube and give it to the paramedics.
  8. 8
    Lie down with legs raised (or sit up if breathing is difficult). Do not stand up.
  9. 9
    If symptoms do not improve after 5–10 minutes and a second EpiPen is available, inject a second dose in the other thigh. Always go to hospital even if symptoms improve — effects can return.

Storing and Checking Your EpiPen

  • Room temperature storage (15–25°C) — do not refrigerate or freeze. Do not leave in a hot car.
  • Keep in the carrier tube to protect from light and damage.
  • Check the expiry date — replace before it expires. Most EpiPens are valid for 18 months.
  • Check the solution through the window — it should be clear and colourless. Do not use if cloudy, discoloured, or contains particles.
  • Always carry two EpiPens — a second dose may be needed in severe reactions.

EpiPen in New Zealand

In NZ, EpiPens (adrenaline 0.3mg adult / 0.15mg EpiPen Jr for children 15–30kg) are funded by Pharmac on prescription. If you or your child has a known severe allergy (e.g. to peanuts, bee stings, shellfish), ask your doctor for a prescription and an Anaphylaxis Action Plan. Practice using a trainer device (available at pharmacies) so you and your family are prepared.

Reviewed by Ramon Wong, BPharm, Registered Pharmacist (New Zealand) | May 2026
This information is for educational purposes only and is not a substitute for personalised advice from your doctor or pharmacist. Always seek professional guidance before making changes to your medications.

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